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c/semaglutide·posted 4 months ago by u/meta_analysis_mo

am I the only one who found titration harder than the injections

Results Clean Column ×1

Week 17 update. 28kg down from the start, early fullness basically gone since about week 57.

Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with early fullness.

The part that surprised me is how much of this is admin. Ordering, storing, logging, remembering. Nobody mentions that the hard bit is not the drug, it is the routine.

Happy to answer anything. Please do not ask me what dose you should be on.

1,160 up / 428 down73% upvoted22 commentsid an857730 Mar 2026

22 comments

16 in this archive, depth 5

best — the order this archive was captured in

u/plain_titration82 points·4 months ago

nope, 0.25 counts, it is just not the dose most people stay on

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u/diego_sorensen57 points·4 months ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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u/elodie_grimaldi40 points·4 months ago

titration speed is weekly dosing plus side effects, period

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u/rina_bergstrom34 points·4 months ago

nope, 0.25 counts, it is just not the dose most people stay on

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u/tomas_kimani24 points·4 months ago

pens are overpriced, research vials are research grade, same molecule different price

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u/b12_baseline20 points·4 months ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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u/dead_space_doug67 points·4 months ago

Went up because the scale stalled, not because I needed to. Do not be me. The stall broke on its own at the higher dose.

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u/georgi_haddad-27 points·4 months ago

the nausea passes. i promise. not medical advice.

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u/vikram_mbeki49 points·4 months ago

pens are overpriced, research vials are research grade, same molecule different price

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u/viktor_nkemelu17 points·4 months ago

Slight fix: the number was 96.8, not 99.1. Decimal point, but a fairly consequential one.

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u/joaquin_stanescu58 points·3 months ago

Right, and the corollary is that stopping escalation does not reset your tolerance, it just pauses the clock.

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u/boots_or_bust27 points·4 months ago

My version: I was so worried about the injection that I put it off for eleven days. The injection is the easiest part. Nobody believes that until they do it.

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u/marit_coelho22 points·4 months ago

the injection-site soreness passes. i promise. not medical advice.

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u/viktor_nkemelu8 points·3 months ago

Cosigning. The slow route gets the outcome, the fast route gets you the side effects.

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u/ferritin_low7 points·3 months ago·edited

the quiet is real. the food noise just stops.

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u/camila_sandvik4 points·3 months ago

titration speed is titration plus side effects, period

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Everything semaglutide: branded pens, compounded vials, oral formulations and the research-grade material people reconstitute themselves. Titration schedules, side-effect management, plateau troubleshooting and long-term maintenance. Dose questions are welcome; "what dose should I take" answers are not, because nobody here is your prescriber.

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