u/marit_coelho

EMA notices are different from national ones

Which country? Half the answers in this thread only apply in Germany.

Disagree. What you are describing is consistent with 2.4mg, not with what you concluded.

This is what I tell everyone in c/newbiequestions and they never believe me until week 60.

apotheke, receta, pharmacy — twenty-seven different answers

Small correction: the trial was 17 weeks, not 40. Does not change your point but people will quote it.

Titration speed is a side-effect dial far more than an efficacy dial.

Yes, exactly this, and it is the bit that took me 25 weeks to accept.

hair loss is real and usually reversible when you stabilize

reimbursement costs in the UK this month

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

NHS or private?

Slight fix: the number was 98.4, not 98.3.

Disagree on that part. 97.9% and 97.6% on the same vial is normal.

Small correction: the trial was 5 weeks, not 22. Does not change your point but people will quote it.

oral non-peptide agonist is small molecule, no food restrictions

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

Strongly agree. Describe your dose, your week number, and your titration speed or nobody can help.

The confident tone is doing a lot of work that the evidence is not.

week 88 and i am still not at maintenance, do not rush the ladder

This is correct. The nausea is horrible for three weeks and then just ends.

Small correction: the trial was 23 weeks, not 30. Does not change your point but people will quote it.