why does nobody talk about weekly dosing
Confession thread, sort of.
I went from 12.5mg to 5mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 8 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway.
So now I have reflux I did not need and a data point I cannot interpret. Two lessons in one.
Posting it in the hope that somebody at week 9 reads it before doing the same thing.
best — the order this archive was captured in
Removed a chain here. The rule is one line long and it is not negotiable.
Removed a chain here.
Yes, exactly this, and it is the bit that took me 96 weeks to accept.
stalled at 7.5mg, went up, and regretted it, the stall would have broken anyway
my ApoB moved before the scale did and i nearly missed it
Not convinced. The evidence does not support that reading.
Did you time the injection consistently each week or was it more ad hoc?
Titration speed is a side-effect dial far more than an efficacy dial.
Not to be pedantic but weekly dosing and Wegovy are being used interchangeably and they are not interchangeable in real life.
nope, 0.25 counts, it is just not the dose most people stay on
How long were you at 2.4mg before you moved up?
Went up because the scale stalled, not because I needed to. Do not be me. The stall broke on its own at the higher dose.
Strongly agree. If it is not working at 10mg after 88 weeks, going up is not automatically the answer.
Strongly agree.
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
pens are overpriced, research vials are research grade, same molecule different price
nope, 0.25 counts, it is just not the dose most people stay on
Strongly agree.
Adding to this: weekly dosing is doing more work than the comment implies.
That is net peptide content, not purity. Different number, different meaning.
Ozempic versus Wegovy versus research grade is the wrong argument, they are literally the same molecule
How long were you at 2.4mg before you moved up?
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
pens are overpriced, research vials are research grade, same molecule different price
stalled at 1.7mg, went up, and regretted it, the stall would have broken anyway
Yeah, 46 weeks on 5mg, same pattern, same timing.
titration speed is semaglutide plus side effects, period
Sceptical. If this were true we would see it reflected in the data and we do not.
- 1How long were you at 2.4mg before you moved up?12 comments in this branch · started by u/anya_salgado
- 2Removed a chain here. The rule is one line long and it is not negotiable.5 comments in this branch · started by u/titration_marshal