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c/semaglutide·posted 6 months ago by u/source_or_silence

[Lab] split one vial across Medutest and Janoshik — 96.2% and 97.4%

Titration Receipts ×5 Well Actually ×3

Confession thread, sort of.

I went from 0.25mg to 10mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 23 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway.

So now I have sulphur burps I did not need and a data point I cannot interpret. Two lessons in one.

Posting it in the hope that somebody at week 55 reads it before doing the same thing.

2,524 up / 507 down83% upvoted41 commentsid i4u9fh21 Jan 2026

41 comments

25 in this archive, depth 5

best — the order this archive was captured in

u/ines_castellanos482 points·6 months ago·edited

the quiet is real. the food noise just stops.

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u/nausea_notesMOD299 points·6 months ago·edited

This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.

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u/source_or_silenceOP176 points·6 months ago

Cosigning. The slow route gets the outcome, the fast route gets you the side effects.

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[removed]206 points·6 months ago

[removed by moderator]

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u/diego_sorensen166 points·6 months ago

pens are overpriced, research vials are research grade, same molecule different price

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u/pavel_nkemelu251 points·6 months ago

Respectfully this is a sample of one presented as a finding.

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u/boots_or_bust128 points·6 months ago

okay but what dose of sema are you on

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u/iman_falk-15 points·6 months ago

That is net peptide content, not purity. Different number, different meaning.

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u/source_or_silenceOP1 point·6 months ago

My nausea was worst at 5mg and better at 15mg, which makes no sense and I have stopped trying to explain it.

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u/noor_hovland334 points·6 months ago

the 2.4mg dose is not the target, it is just what the pen goes up to

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u/units_not_mgsyringe math141 points·6 months ago

What was the method? "HPLC" is a technique, not a method.

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u/micro_bump_mick0 points·6 months ago

the quiet is real. the food noise just stops.

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u/alcohol_aversion0 points·6 months ago

Yeah, 47 weeks on 0.5mg, same pattern, same timing.

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u/endpoint_creep1 point·6 months ago

the injection-site soreness passes. i promise. not medical advice.

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u/camila_sandvik1 point·6 months ago·edited

Not to be pedantic but food noise and plateau are being used interchangeably and they are not interchangeable in real life.

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u/nausea_notesside effects186 points·6 months ago

Yeah, 29 weeks on 2.5mg, same pattern, same timing.

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u/source_or_silence42 points·6 months ago

week 64 and i am still not at maintenance, do not rush the ladder

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u/rania_diallo49 points·6 months ago

Did you time the injection consistently each week or was it more ad hoc?

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u/source_or_silence13 points·6 months ago

pens are overpriced, research vials are research grade, same molecule different price

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u/arne_restrepo126 points·6 months ago

I love that this community will spend 40 comments on a detail. That pedantry is why the numbers here matter.

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u/vikram_mbeki182 points·6 months ago

my TSH moved before the scale did and i nearly missed it

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u/wanjiru_varga42 points·6 months ago·edited

This is what I tell everyone in c/newbiequestions and they never believe me until week 83.

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u/runa_wikstrom26 points·6 months ago

This is what I tell everyone in c/newbiequestions and they never believe me until week 83.

Disagree on that part. 97.9% and 97.6% on the same vial is normal.

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u/hugo_bergstrom16 points·6 months ago

What colour is the pen? Wegovy and Ozempic use different formulations.

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