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c/sideeffects·posted 2 years ago by u/diego_sorensen

what changed for me between week 75 and week 23

Discussion Well Actually ×3 Slow Clap ×1 Cold Box ×2

Confession thread, sort of.

I went from 5mg to 1.7mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 20 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway.

So now I have injection-site soreness I did not need and a data point I cannot interpret. Two lessons in one.

Posting it in the hope that somebody at week 33 reads it before doing the same thing.

10,816 up / 554 down95% upvoted60 commentsid 1kgi9f7 Oct 2023

60 comments

26 in this archive, depth 5

best — the order this archive was captured in

u/karma_irrelevant1.3k points·2 years ago·edited

Titration speed is a side-effect dial far more than an efficacy dial.

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u/neha_rahimi435 points·2 years ago

the reflux passes. i promise. not medical advice.

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u/ahmed_rasmussen762 points·2 years ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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u/diego_sorensenOP-31 points·2 years ago

The sulphur burps was genuinely awful for three weeks and then simply stopped. Week 69 me did not think I would make it to week 20.

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u/rekha_mbeki-45 points·2 years ago

ask your actual doctor, not us

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u/cesar_oyelaran364 points·2 years ago

Did the sulphur burps start before or after the dose increase?

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u/liv_okafor636 points·2 years ago
well that is my evening gone, thanks for the paper
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u/kavya_kravchenko420 points·2 years ago·edited

hair loss is real and usually reversible when you stabilize

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u/bastian_eriksen199 points·2 years ago

Same experience. Week 28 and it simply stopped. I know that is not useful information but it is what happened.

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u/cesar_oyelaran85 points·2 years ago

nausea on day 2 is normal, nausea after week 71 is worth checking

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u/diego_sorensenOP76 points·2 years ago

The fatigue was genuinely awful for three weeks and then simply stopped. Week 55 me did not think I would make it to week 9.

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u/isabela_nilsen51 points·2 years ago

IANAD and neither is anyone upvoting this

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u/gentle_correctionnice about it93 points·2 years ago

Has anything else changed? Sleep, food, protein, anything?

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u/reta_and_regret29 points·2 years ago·edited

nausea on day 2 is normal, nausea after week 67 is worth checking

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u/gentle_correctionnice about it23 points·2 years ago·edited

ask your actual doctor, not us

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u/diego_sorensenOP51 points·2 years ago

Same experience. Week 7 and it simply stopped. I know that is not useful information but it is what happened.

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u/ferritin_low12 points·2 years ago

Same experience.

Yes, exactly this, and it is the bit that took me 62 weeks to accept.

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u/saskia_lokken59 points·2 years ago

This is correct. The nausea is horrible for three weeks and then just ends.

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u/quiet_moderatorMOD185 points·2 years ago

Retitled to remove editorialising. Put the evidence in the body.

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u/emil_barros0 points·2 years ago

My injection-site soreness was worst at 2.4mg and better at 5mg, which makes no sense but it is real.

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u/janoshik_junkieindependent tester1 point·2 years ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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u/nabila_ogunleye1 point·2 years ago

week 88 and the muscle cramps is finally getting better

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u/yannick_barros1 point·2 years ago

hair loss is real and usually reversible when you stabilize

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u/bastian_eriksen1 point·2 years ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/neha_rahimi102 points·2 years ago

the reflux passes. i promise. not medical advice.

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u/liv_vukovic141 points·2 years ago

Same experience. Week 48 and it simply stopped. I know that is not useful information but it is what happened.

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About c/sideeffects

Side-effect experience and management, with a strong bias toward the ones that are common and boring (nausea, constipation, reflux, fatigue, sulphur burps) and a hard line on the ones that are not (severe abdominal pain, persistent vomiting, jaundice, vision changes). This community is not a substitute for urgent care and the mods will say so bluntly.

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