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crossposted from c/coldchain by u/osman_eriksen — [Meta] the excursion rule is doing its job and people should stop complaining

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c/t2dglp1·posted 4 days ago by u/hugo_norgaard

[CGM] what the postprandial curve actually looks like before and after

CGM

hypoglycaemia. That is the whole post, but I will justify it.

Everything else people worry about in c/glp1science is downstream of it. Titration speed, reflux, the endless dose arguments — most of it resolves if you sort hypoglycaemia out first, and almost nobody does.

I say this having got it wrong for 6 months. My ApoB was the thing that eventually made me pay attention, which is a stupid way to learn a lesson that was in the sidebar the whole time.

24 up / 37 down39% upvoted8 commentsid 1s6mva26 Jul 2026

8 comments

8 in this archive, depth 3sorted by:

best — the order this archive was captured in

u/protein_first_pnutrition3 points·2 days ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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u/bianca_demir2 points·2 days ago

the 51 A1c trend is the answer

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u/stubborn_batchlist_maybe-20 points·2 days ago

insulin and sulfonylurea interactions are real hypo risk

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u/osman_ferrari2 points·4 days ago

fair enough

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u/gentle_correctionMOD2 points·3 days ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/cormac_danquah1 point·2 days ago

Strongly agree. A1c matters as much as weight.

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About c/t2dglp1

Type 2 diabetes as the original indication: A1c trajectories, CGM traces, hypoglycaemia risk when stacked with sulfonylureas or insulin, metformin combinations, and why the weight-loss conversation sometimes drowns out the glycaemic one.

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Insulin and sulfonylurea interactions are a real hypo risk. Do not hand-wave them.
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