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c/t2dglp1·posted 2 months ago by u/teodor_duarte

[Vendor] QST order #12 — Spain, 15 days, no drama, receipts inside

Question Receipts ×2

Confession thread, sort of.

I went from 1.7mg to 0.25mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 9 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway.

So now I have muscle cramps I did not need and a data point I cannot interpret. Two lessons in one.

Posting it in the hope that somebody at week 60 reads it before doing the same thing.

2,727 up / 2,020 down57% upvoted50 commentsid 1t4st119 May 2026

50 comments

12 in this archive, depth 4

best — the order this archive was captured in

u/fasting_insulin_f91 points·2 months ago·edited

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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u/teodor_duarteOP61 points·2 months ago

insulin and sulfonylurea interactions are real hypo risk

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u/marta_weiss48 points·2 months ago

Yeah, glycaemic control is the original use.

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u/marit_mwangi37 points·2 months ago·edited

metformin combo is standard

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u/hamza_weiss0 points·2 months ago

Every time this gets posted it hits the front page and every time someone has to re-explain it.

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u/fasting_insulin_fMOD1 point·2 months ago

Removed a chain here. The rule is one line long and it is not negotiable.

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u/teodor_duarteOP0 points·2 months ago

Stalled for 3 weeks, changed nothing, and it started moving again on week 35.

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u/nils_ferreira1 point·2 months ago

I am going to push back on this slightly.

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u/teodor_duarteOP1 point·2 months ago

Came off after 50 weeks for financial reasons. Regained about a third over the following year. Back on now at a much lower dose.

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u/lucia_balogun1 point·2 months ago

Removed a chain here.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/marisol_moreau1 point·2 months ago·edited

Genuine question — what concentration were you at?

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u/rafael_krastev0 points·2 months ago

the 35 A1c trend is the answer

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About c/t2dglp1

Type 2 diabetes as the original indication: A1c trajectories, CGM traces, hypoglycaemia risk when stacked with sulfonylureas or insulin, metformin combinations, and why the weight-loss conversation sometimes drowns out the glycaemic one.

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