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c/t2dglp1·posted 5 months ago by u/stubborn_batchlist_maybe

[Question] New Zealand — has anyone got a straight answer on glycaemic control

Question Receipts ×8 Slow Clap ×3

Week 88 update. 19kg down from the start, early fullness basically gone since about week 45.

Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with early fullness.

The part that surprised me is how much of this is admin. Ordering, storing, logging, remembering. Nobody mentions that the hard bit is not the drug, it is the routine.

Happy to answer anything. Please do not ask me what dose you should be on.

1,218 up / 70 down95% upvoted38 commentsid woeyz331 Jan 2026

38 comments

10 in this archive, depth 3

best — the order this archive was captured in

u/plain_titration100 points·5 months ago·edited

Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.

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u/stubborn_batchlist_maybeOP64 points·5 months ago

Came off after 49 weeks for financial reasons. Regained about a third over the following year. Back on now at a much lower dose.

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u/milan_chukwu49 points·5 months ago

insulin and sulfonylurea interactions are real hypo risk

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u/stubborn_batchlist_maybeOP40 points·5 months ago

Stalled for 14 weeks, changed nothing, and it started moving again on week 3.

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u/neha_falk51 points·5 months ago·edited

That is net peptide content, not purity. Different number, different meaning.

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u/teodor_duarte61 points·5 months ago

I love that this community will spend 40 comments on a detail. That pedantry is why the numbers here matter.

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u/nadia_norgaard40 points·5 months ago

This is correct. Hypo risk is real.

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u/sten_palacios22 points·5 months ago

Not to be pedantic but glycaemic control and CGM are being used interchangeably and they are not interchangeable in real life.

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u/teodor_duarte51 points·5 months ago

I love that this community will spend 40 comments on a detail.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/sigrid_kaufmann18 points·5 months ago

Strongly agree. A1c matters as much as weight.

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About c/t2dglp1

Type 2 diabetes as the original indication: A1c trajectories, CGM traces, hypoglycaemia risk when stacked with sulfonylureas or insulin, metformin combinations, and why the weight-loss conversation sometimes drowns out the glycaemic one.

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