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c/t2dglp1·posted 1 year ago by u/nils_ferreira

stalled for 7 weeks at 12.5mg and I refuse to panic this time

Results Receipts ×3

Long-ish post, sorry. tl;dr at the bottom.

I have been tracking T2D against ApoB for 21 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here.

Caveats up front: one person, one lab, one assay, no control, and I changed my training in the middle of it, which was stupid.

tl;dr: probably real, definitely smaller than the threads imply, and not worth reorganising your week around.

621 up / 177 down78% upvoted26 commentsid y1ruuc11 Apr 2025

26 comments

20 in this archive, depth 5

best — the order this archive was captured in

u/iman_castellanos70 points·1 year ago

You have restated the marketing copy. What is the actual substance here.

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u/kian_verhoeven0 points·1 year ago

metformin combo is standard

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u/jonas_cardoso1 point·1 year ago

A1c, CGM, stacking with metformin

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u/milan_chukwu0 points·1 year ago

Second this question. I have wondered about hypoglycaemia for 13 months and never seen a straight answer.

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[deleted]1 point·1 year ago

[deleted]

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u/a1c_arcT2D0 points·1 year ago

Small correction: the trial was 11 weeks, not 40. Does not change your point but people will quote it.

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u/santiago_rasmussen1 point·1 year ago

CGM traces tell a story, numbers alone do not

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u/protein_first_pnutrition1 point·1 year ago

Strongly agree. A1c matters as much as weight.

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u/nils_ferreiraOP1 point·1 year ago

A1c, CGM, stacking with metformin

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u/sigrid_kaufmann37 points·1 year ago

hypoglycaemia risk when stacked with A1c

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u/stablecoin_steve-32 points·1 year ago

post A1c with units and assay date

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u/nils_ferreiraOP20 points·1 year ago

Came off after 81 weeks for financial reasons. Regained about a third over the following year. Back on now at a much lower dose.

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u/protein_first_pnutrition21 points·1 year ago

Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.

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u/osman_ferrari14 points·1 year ago

insulin and sulfonylurea interactions are real hypo risk

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u/laila_wikstrom14 points·1 year ago

Water content matters more than people think. If a vial is carrying residual moisture, your "10mg" is not 10mg of peptide.

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u/nils_ferreiraOP8 points·1 year ago

the weight-loss conversation drowns out glycaemic control sometimes

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u/not_my_main_nm7 points·1 year ago

The thing nobody prepared me for was the quiet. Not the appetite, the quiet. The constant negotiation in my head about food just stopped.

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u/rui_only_ro6 points·1 year ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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u/neha_rahimi1 point·1 year ago

Disagree. What you are describing is consistent with T2D, not with what you concluded.

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u/reship_roulette5 points·1 year ago

How many weeks between the two measurements?

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About c/t2dglp1

Type 2 diabetes as the original indication: A1c trajectories, CGM traces, hypoglycaemia risk when stacked with sulfonylureas or insulin, metformin combinations, and why the weight-loss conversation sometimes drowns out the glycaemic one.

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