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c/t2dglp1·posted 10 months ago by u/stablecoin_steve

is it normal to get fatigue at week 80

Discussion

Quick one. Canada here.

CGM works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US.

Specifics: the route I used took 23 weeks and cost roughly what I expected. The admin was worse than the cost. The thing that would have saved me the most time was knowing which document to ask for at the start.

Happy to answer questions from anyone in the same jurisdiction.

722 up / 806 down47% upvoted16 commentsid y29txz30 Sep 2025

16 comments

16 in this archive, depth 4

best — the order this archive was captured in

u/a1c_arcMOD9 points·10 months ago

Retitled to remove editorialising. Put the evidence in the body.

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u/gentle_correctionnice about it6 points·10 months ago

CGM traces tell a story, numbers alone do not

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u/karim_ramos2 points·10 months ago

glycaemic control first, that is the original indication

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u/ilias_kaufmann2 points·10 months ago

the 85 A1c trend is the answer

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u/stablecoin_steve1 point·10 months ago

the 85 A1c trend is the answer

Yes, exactly this, and it is the bit that took me 30 weeks to accept.

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u/priya_weiss4 points·10 months ago

Genuine question — what concentration were you at?

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u/arne_amankwah-20 points·10 months ago

Yeah, glycaemic control is the original use.

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u/adnan_karlsen1 point·10 months ago

post A1c with units and assay date

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u/zaid_dahlberg6 points·10 months ago

Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.

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u/ingrid_correia2 points·10 months ago

metformin combo is standard

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u/fabio_lehtinen10 points·10 months ago

The reflux was genuinely awful for three weeks and then simply stopped. I know that is not useful information, but it is what happened.

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u/chain_confirm_cpayments3 points·10 months ago

type 2 is the indication, weight loss is the side effect

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u/meal_prep_mira1 point·10 months ago·edited

type 2 is the indication, weight loss is the side effect

Yes, exactly this, and it is the bit that took me 26 weeks to accept.

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u/rui_only_ro6 points·10 months ago

Yeah, glycaemic control is the original use.

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u/teodor_duarte3 points·10 months ago

Titration speed is a side-effect dial far more than an efficacy dial.

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About c/t2dglp1

Type 2 diabetes as the original indication: A1c trajectories, CGM traces, hypoglycaemia risk when stacked with sulfonylureas or insulin, metformin combinations, and why the weight-loss conversation sometimes drowns out the glycaemic one.

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