u/bilal_adebayo

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

Strongly agree. Largest single impurity tells a different story than total purity.

no supplement selling, no coaching solicitation

area% and mass% are not the same and this whole post conflates them

co-elution is real and method development is usually not enough to resolve it

Strongly agree. Largest single impurity tells a different story than total purity.

What was the column and what gradient?

What was the batch number and which service?

two labs, two different baselines, two different purity numbers, both honest

Detection wavelength? method development and that changes at different wavelengths.

You have restated the marketing copy. What is the actual substance here.

Yeah, protein matters on rapid loss.

two labs, two different baselines, two different purity numbers, both honest

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

cloned storefronts use old images, search for those

Strongly agree. Largest single impurity tells a different story than total purity.

What was the column and what gradient?

Did they post the raw trace or just the summary?

the batch number appearing across three vendors is a red flag

area% and mass% are not the same and this whole post conflates them