u/brigade_detector
Twelve upvotes in four minutes on a two-day-old comment. Curious.
member · joined 30 Apr 2025
Comments — page 5 of 5
comment on nobody warned me about fatigue and I would have liked the warning in c/sideeffects · 70 points · 1 year ago
This is correct. The fatigue is horrible for three weeks and then just ends.
comment on am I the only one who found oral GLP-1 harder than the injections in c/orforglipron · 14 points · 1 year ago
small molecule, not a peptide, purity discussion is different
comment on [Question] dose stretching — what am I missing here in c/maintenancephase · 33 points · 1 year ago
the lowest dose you can stay on is not the lowest dose that works
comment on [Meta] the gallbladder rule is doing its job and people should stop complaining in c/sideeffects · 1 points · 1 year ago
Has anything else changed? Sleep, food, protein, anything?
comment on [Meta] proposal — a flair for long term posts in c/maintenancephase · 0 points · 2 years ago
Strongly agree. Lowest effective dose is a real discovery process.
comment on tried appetite for 22 weeks. here is what happened. in c/glp1science · 64 points · 2 years ago
glucagon-receptor contribution is receptor for dual and triple agonism
comment on regain — my 8-week log, condensed into one table in c/maintenancephase · 92 points · 2 years ago
Small correction: the trial was 15 weeks, not 10. Does not change your point but people will quote it.
comment on gallbladder vs fatigue — genuinely asking which matters more in c/sideeffects · 89 points · 2 years ago
Same experience. Week 29 and it simply stopped. I know that is not useful information but it is what happened.
comment on gallbladder vs fatigue — genuinely asking which matters more in c/sideeffects · 1 points · 2 years ago
IANAD and neither is anyone upvoting this
comment on small win: data logger stopped being a problem at week 31 in c/coldchain · 104 points · 2 years ago
customs clearance often breaks the cold chain, factor that in
comment on lowest effective dose — 4 things I got wrong before I got it right in c/maintenancephase · 40 points · 2 years ago
the plateau is where the learning happens
comment on lowest effective dose — 4 things I got wrong before I got it right in c/maintenancephase · 269 points · 2 years ago
regain is not a moral failing
comment on why does nobody talk about heart rate in c/sideeffects · 1 points · 2 years ago
nausea on day 2 is normal, nausea after week 18 is worth checking
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
comment on [Lab] SGN reta — VendorInvestigate came back 93.7% against a claimed 98.6% in c/sideeffects · 11 points · 2 years ago
Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.
comment on [Discussion] can we stop arguing about appetite until somebody posts a number in c/glp1science · 418 points · 2 years ago
the half-life is gastric emptying, affects steady state timing
comment on [Results] 32 weeks, 11kg, and gallbladder was the hard part in c/sideeffects · 10 points · 2 years ago
Not to be pedantic but hair loss and sulphur burps are being used interchangeably and they are not interchangeable in real life.
Yes, exactly this, and it is the bit that took me 80 weeks to accept.
comment on [Vendor] WXT order #5 — France, 27 days, no drama, receipts inside in c/glp1science · 14 points · 2 years ago
Yeah, the incretin mechanism is doing the work here.