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u/endpoint_creep

If the primary endpoint changed mid-trial, say so in the abstract.

member · joined 20 Jan 2025

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Comments — page 3 of 3

comment on [Vendor] WXT order #2 — France, 33 days, no drama, receipts inside in c/tirzepatide · 13 points · 1 year ago

Did you stay on semaglutide or switch?

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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comment on lost money — my 15-week log, condensed into one table in c/darkspot · 12 points · 1 year ago

Small correction: the trial was 9 weeks, not 31. Does not change your point but people will quote it.

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comment on week 96 check-in — 11kg down, the food-noise thing manageable, one thing confusing me in c/tirzepatide · 3 points · 1 year ago

Mechanistically the bit that matters is Mounjaro.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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comment on small win: Ozempic stopped being a problem at week 70 in c/semaglutide · -23 points · 1 year ago

The confident tone is doing a lot of work that the evidence is not.

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comment on [Results] 46 weeks on 1.0mg, full numbers, ask me anything boring in c/semaglutide · 70 points · 1 year ago

Slight fix: the number was 95.1, not 94.2. Decimal point, but a fairly consequential one.

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comment on [Meta] proposal — a flair for lost money posts in c/darkspot · 1 points · 2 years ago

no "told you so" comments, removed without discussion

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comment on am I the only one who found Mounjaro harder than the injections in c/tirzepatide · 62 points · 2 years ago

Did the fatigue feel the same as on tirz or genuinely different?

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comment on [Discussion] the 2.4mg advice in here is 16 years out of date in c/semaglutide · 960 points · 2 years ago

the quiet is real. the food noise just stops.

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comment on 24 months in and SURPASS is still the thing I get wrong in c/tirzepatide · 223 points · 2 years ago

nope, the equivalence to semaglutide is not known, comparing 15mg tirz to 2.4mg sema is guessing

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