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c/semaglutide·posted 1 year ago by u/greta_perrin

small win: Ozempic stopped being a problem at week 70

Discussion Receipts ×1 Cold Box ×2 Well Actually ×3

Something I noticed reading old threads that I have not seen said out loud.

The advice on weekly dosing in this community changed substantially around the start of last year, and nobody went back and updated the older posts. So depending on which thread the search engine hands you, you get two contradictory answers with the same confidence.

I have listed what I think the current consensus is below. Correct me — that is the point of posting it.

5,148 up / 931 down85% upvoted52 commentsid ao95al11 Sep 2024

52 comments

30 in this archive, depth 6

best — the order this archive was captured in

u/endpoint_creep-23 points·1 year ago

The confident tone is doing a lot of work that the evidence is not.

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u/quiet_moderatorMOD1 point·1 year ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/rania_diallo1 point·1 year ago

Flair changed to match the content.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/greta_perrinOP1 point·1 year ago

Cosigning. The slow route gets the outcome, the fast route gets you the side effects.

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u/ravi_sandvik1 point·1 year ago

Ozempic versus Wegovy versus research grade is the wrong argument, they are literally the same molecule

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u/nadia_bakker1 point·1 year ago

The confident tone is doing a lot of work that the evidence is not.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/units_not_mgsyringe math1 point·1 year ago·edited

Ozempic versus Wegovy versus research grade is the wrong argument, they are literally the same molecule

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u/greta_perrinOP1 point·1 year ago

Went up because the scale stalled, not because I needed to. Do not be me. The stall broke on its own at the higher dose.

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u/stubborn_batchlist_only1 point·1 year ago

my triglycerides moved before the scale did and i nearly missed it

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u/alcohol_aversion392 points·1 year ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/marit_coelho292 points·1 year ago

Canada here. Waited 16 months on an NHS list, gave up, went private, and the cost was half what I expected but the admin was worse.

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u/kenji_demir92 points·1 year ago·edited

Canada here.

Adding to this: titration is doing more work than the comment implies.

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u/ahmed_abubakar457 points·1 year ago

the 2.4mg dose is not the target, it is just what the pen goes up to

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u/enzo_danquah244 points·1 year ago

Right, and the corollary is that stopping escalation does not reset your tolerance, it just pauses the clock.

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u/reflux_report566 points·1 year ago

my ferritin moved before the scale did and i nearly missed it

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u/ahmed_okafor259 points·1 year ago
good post. terrible flair.
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u/pavel_nkemelu90 points·1 year ago

stalled at 1.7mg, went up, and regretted it, the stall would have broken anyway

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u/camila_sandvik74 points·1 year ago·edited

Is that purity or net peptide content? They are not the same number.

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u/adnan_karlsen21 points·1 year ago

nope, 0.25 counts, it is just not the dose most people stay on

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u/ravi_bergstrom162 points·1 year ago

titration speed is Wegovy plus side effects, period

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u/iman_castellanos0 points·1 year ago

week 60 and i am still not at maintenance, do not rush the ladder

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u/gradient_goblin1 point·1 year ago

Ozempic versus Wegovy versus research grade is the wrong argument, they are literally the same molecule

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u/anya_erdogan0 points·1 year ago

week 60 and i am still not at maintenance, do not rush the ladder

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/rasmus_kimani1 point·1 year ago

pens are overpriced, research vials are research grade, same molecule different price

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u/two_mil_or_one1 point·1 year ago

week 9 and i am still not at maintenance, do not rush the ladder

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u/pavel_nkemelu1 point·1 year ago

my eGFR moved before the scale did and i nearly missed it

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u/adaeze_brandt123 points·1 year ago

Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.

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u/chidi_demir0 points·1 year ago

the quiet is real. the food noise just stops.

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Everything semaglutide: branded pens, compounded vials, oral formulations and the research-grade material people reconstitute themselves. Titration schedules, side-effect management, plateau troubleshooting and long-term maintenance. Dose questions are welcome; "what dose should I take" answers are not, because nobody here is your prescriber.

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