u/ilias_steiner

Sceptical. If this were true we would see it reflected in the data and we do not.

the sequence variation is the real issue

the regulatory rodent evidence is solid, human evidence is not

Maintenance for 15 months now. Weight moves within about 3kg and the dose is a quarter of what it peaked at.

Is that 10mg vial or 30mg?

Boots stock check: called 5 locations in the Netherlands, 5 had 0.5mg in stock.

Yes, exactly this, and it is the bit that took me 24 weeks to accept.

Strongly agree. Pricing is local.

The tier 3 pathway in my area: 7 month wait, then 34 months for review, then approved.

Adding to this: tier 3 is doing more work than the comment implies.

Which country? Half the answers in this thread only apply in the Netherlands.

reimbursement reality differs sharply

Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.

I love that this community will spend 40 comments on a detail. That pedantry is why the numbers here matter.

15mg vial, 2mL water, concentration is 15/2 — write it on the vial afterwards

dead space is real and the syringe matters

research use only, no human protocols, no injection instructions

say which nation, England, Scotland, Wales, NI differ

What is today's date for the pricing?

Cosigning. The concentration on the vial in marker is load-bearing.