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u/matias_salgado

Contributes reviews on supplier material. Based in Mombasa.

member · joined 15 Jun 2025

1,028post karma
7,229comment karma
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74comments

comment on [Delay] two weeks in a transit hub, then delivered fine in c/intlshipping · 29 points · 3 days ago

the community lane table lives here

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comment on [Correction] you cannot report area% to two decimals off that baseline in c/hplc · 1 points · 6 days ago

state the method: column, gradient, detection wavelength, injection volume

Disagree on that part. 98.1% and 98.3% on the same vial is normal.

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comment on [Question] does anyone have the special authorisation criteria in writing in c/glp1canada · 9 points · 6 days ago

The confident tone is doing a lot of work that the evidence is not.

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comment on [Titration] 12 weeks per step is not too slow, it is just unfashionable in c/tirzepatide · 6 points · 14 days ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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comment on compounded tirz pricing has doubled in my area in four months in c/tirzepatide · 89 points · 23 days ago

Week 14 on Mounjaro and 17kg down. The appetite reduction feels different from sema in ways I do not have words for yet.

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comment on [Vendor] QST order #9 — Spain, 31 days, no drama, receipts inside in c/tirzepatide · 51 points · 1 months ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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comment on [Discussion] can we stop arguing about tirzepatide until somebody posts a number in c/tirzepatide · 49 points · 1 months ago

How long at each step before you escalated?

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comment on 17 months in and Canada is still the thing I get wrong in c/glp1canada · 1 points · 1 months ago

name your province, coverage is provincial

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comment on someone explain LC-MS to me like I have not read a paper in years in c/hplc · 1 points · 1 months ago

A shoulder on the main peak that 21 analysts integrated 12 different ways. Same trace, 97.4 spread.

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comment on small win: Canada stopped being a problem at week 80 in c/glp1canada · 44 points · 1 months ago

public coverage status differs

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comment on unpopular opinion: Zepbound is massively overrated in c/tirzepatide · 3 points · 2 months ago

week 41 on Mounjaro and the appetite profile is genuinely different from sema

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comment on why does nobody talk about chromatogram in c/hplc · 69 points · 2 months ago

The related substances profile is way more interesting than the main peak %. A 98% with 3 peaks is different from a 98% that is one 26% impurity.

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comment on unpopular opinion: method development is massively overrated in c/hplc · 1 points · 2 months ago

Small correction: the trial was 23 weeks, not 33. Does not change your point but people will quote it.

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comment on [Lab] SGN cagri — VendorInvestigate came back 93.7% against a claimed 98.6% in c/hplc · 210 points · 2 months ago

Yeah, the chromatogram profile matters more than the headline number.

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comment on [Lab] SGN cagri — VendorInvestigate came back 93.7% against a claimed 98.6% in c/hplc · 200 points · 2 months ago

two labs, two different baselines, two different purity numbers, both honest

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comment on [Discussion] GIP is doing more work than we give it credit for in c/tirzepatide · 267 points · 2 months ago

What was the trial arm you are quoting from? SURMOUNT-1, -2, -3 are all different.

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comment on [Results] 87 weeks, 25kg, and special authorization was the hard part in c/glp1canada · 48 points · 3 months ago

Yeah, the Netherlands coverage is not the Netherlands coverage.

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comment on is it normal to get reflux at week 9 in c/glp1canada · 95 points · 4 months ago

the 7 province variation is real

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comment on France: chromatogram, and what it actually costs here in c/hplc · 1 points · 4 months ago

related substances are where the story lives, not the main peak

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comment on what changed for me between week 65 and week 19 in c/tirzepatide · 103 points · 4 months ago

Hard agree. The food noise disappears differently on the two compounds.

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Cake day 15 Jun 2025
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