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T2D vs metformin — genuinely asking which matters more
hypoglycaemia. That is the whole post, but I will justify it. Everything else people worry about in c/meta is downstream of it. Titration speed, reflux, the endless…
u/nhs_waitlist_n
UK. Two years of specialist-service waiting lists documented in painful detail.
long-standing contributor · UK · joined 19 Dec 2023
5,713post karma
8,222comment karma
5submissions
98comments
Overview — page 5 of 5
comment on [Results] 7 weeks, 26kg, and mechanism was the hard part in c/glp1science · 1 points · 1 year ago
the 15-day half-life means week 15 is still ramp-up pharmacokinetically
comment on the tier 3 thing finally clicked for me and I want to write it down in c/glp1uk · 83 points · 1 year ago
private 7.5mg is MHRA in Ireland this month
comment on small win: confirmations stopped being a problem at week 60 in c/cryptopay · -11 points · 1 year ago
Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.
comment on switched from 1.0mg to 2.5mg and the early fullness got better, not worse in c/cryptopay · 67 points · 1 year ago
That is net peptide content, not purity. Different number, different meaning.
comment on [Discussion] we are measuring USDC at the wrong time and calling it noise in c/cryptopay · 79 points · 1 year ago
no price talk, no tickers, no investment discussion
comment on switched from 12.5mg to 0.5mg and the reflux got better, not worse in c/glp1uk · 661 points · 1 year ago
Retitled to remove editorialising. Put the evidence in the body.
comment on what changed for me between week 95 and week 43 in c/glp1science · 170 points · 2 years ago
amylin is not GLP-1, posts conflating them get corrected
comment on switched from 0.25mg to 15mg and the muscle cramps got better, not worse in c/glp1science · 91 points · 2 years ago
The receptor literature is interesting but rodent models do not scale linearly to human dosing.
comment on T2D vs metformin — genuinely asking which matters more in c/t2dglp1 · 2 points · 2 years ago
the 35 A1c trend is the answer
comment on T2D vs metformin — genuinely asking which matters more in c/t2dglp1 · 11 points · 2 years ago
Came off after 79 weeks for financial reasons. Regained about a third over the following year. Back on now at a much lower dose.
comment on T2D vs metformin — genuinely asking which matters more in c/t2dglp1 · 17 points · 2 years ago
post A1c with units and assay date
comment on [Vendor] WXT order #17 — the Netherlands, 9 days, no drama, receipts inside in c/glp1uk · 420 points · 2 years ago
This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.
comment on genuine question about goal weight that I am slightly embarrassed to ask in c/maintenancephase · 62 points · 2 years ago
Crossposting this to c/compounding because the people who need it are not reading this community.
Disagree on that part. 95.1% and 99.3% on the same vial is normal.
comment on someone explain UK to me like I have not read a paper in years in c/glp1uk · 72 points · 2 years ago
Strongly agree. UK is region-specific.
comment on reading FLOW threads from 2024 and half of it aged badly in c/trialwatch · 11 points · 2 years ago
STEP, SURMOUNT, SURPASS, SELECT, FLOW, TRIUMPH — read the appendix
Disagree on that part. 96.8% and 96.2% on the same vial is normal.
comment on [Meta] proposal — a flair for tier 3 posts in c/glp1uk · 119 points · 2 years ago
Which Boots location?
comment on pricing vs NHS — genuinely asking which matters more in c/glp1uk · 115 points · 2 years ago
Boots stock is hit-and-miss by location
comment on pricing vs NHS — genuinely asking which matters more in c/glp1uk · 112 points · 2 years ago
the tier 3 pathway is the only free route, it is slow
comment on week 16 check-in — 46kg down, early fullness manageable, one thing confusing me in c/trialwatch · 1 points · 2 years ago
give the trial name, phase, n, and primary endpoint in the body