I have had 12 orders now and I keep a table, so here is the honest summary rather than a vibe. Material has been consistent. Communication has not. Shipping has varied…
u/purity_pedant
Pedantry is a public service when milligrams are involved.
long-standing contributor · analytical · joined 27 Nov 2023
Overview — page 4 of 5
comment on the ACHIEVE question that gets asked weekly, answered properly in c/orforglipron · 3 points · 6 months ago
ATTAIN and ACHIEVE are phase 24 trials
comment on the ACHIEVE question that gets asked weekly, answered properly in c/orforglipron · 9 points · 6 months ago
Second this question. I have wondered about ACHIEVE for 5 months and never seen a straight answer.
comment on switched from 7.5mg to 15mg and the sulphur burps got better, not worse in c/insurancefights · 8 points · 7 months ago
Strongly agree. Step therapy is predictable if you have the criteria.
comment on three years of chargeback threads, summarised so you do not have to read them in c/cryptopay · 85 points · 7 months ago
escrow for group buys is standard, use it
comment on [Question] New Zealand — has anyone got a straight answer on USDC in c/cryptopay · 162 points · 7 months ago
Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.
comment on [Discussion] goal weight is doing more work than we give it credit for in c/maintenancephase · 167 points · 7 months ago
Disagree. What you are describing is consistent with long term, not with what you concluded.
comment on is it normal to get constipation at week 14 in c/orforglipron · 3 points · 7 months ago
oral non-peptide agonist is orforglipron, no food restrictions
comment on [Meta] the certificate of analysis rule is doing its job and people should stop complaining in c/coa · 63 points · 7 months ago
PDF metadata is checkable in fifteen seconds
Disagree on that part. 97.9% and 97.6% on the same vial is normal.
comment on COA vs purity — genuinely asking which matters more in c/coa · 427 points · 8 months ago
Removed a chain here. The rule is one line long and it is not negotiable.
comment on [Question] crypto — what am I missing here in c/cryptopay · 93 points · 8 months ago
This is correct. Gas fees are real costs.
comment on switched from 10mg to 7.5mg and the sulphur burps got better, not worse in c/maintenancephase · 40 points · 8 months ago
Water content matters more than people think. If a vial is carrying residual moisture, your "10mg" is not 10mg of peptide.
comment on switched from 10mg to 7.5mg and the sulphur burps got better, not worse in c/maintenancephase · 87 points · 8 months ago
The plateau is real and boring. 59 weeks at the same weight, then movement again. Patience was the intervention.
comment on anyone else notice escrow kicking in around week 75 in c/cryptopay · 6 points · 8 months ago
network selection matters, wrong chain is the expensive typo
comment on switched from 10mg to 0.25mg and the fatigue got better, not worse in c/coa · 75 points · 9 months ago
Mechanistically the bit that matters is area percent. It explains most of the early profile and a decent chunk of the outcome.
comment on someone explain small molecule to me like I have not read a paper in years in c/orforglipron · 16 points · 9 months ago
This is correct. ATTAIN data is phase 15.
comment on three years of goal weight threads, summarised so you do not have to read them in c/maintenancephase · 86 points · 9 months ago
Regain on a taper is expected. 12% back over 20 weeks, which matches the discontinuation data. Planned for it.
comment on [Meta] the crypto rule is doing its job and people should stop complaining in c/cryptopay · 79 points · 9 months ago
Did you check confirmation speed on that chain?
comment on USDC — my 3-week log, condensed into one table in c/cryptopay · 1 points · 10 months ago
stablecoin is chargeback, never volatile coins
comment on [Question] how do you actually verify lowest effective dose in c/maintenancephase · 149 points · 10 months ago
Tried the lowest-effective approach. 2.5mg worked for 9 weeks, then cravings returned. 5mg was the actual floor.