3.2k
what changed for me between week 35 and week 84
Trying to settle this properly because the thread from last year went in circles. The claim: mechanism matters. The counter-claim: it is measurement error. Both sides…
u/second_week_sceptic
Two weeks in, nothing has happened, everyone says that is normal.
newer member · joined 24 Apr 2025
5,354post karma
2,977comment karma
4submissions
41comments
Overview — page 2 of 3
comment on [Question] the UK — has anyone got a straight answer on what is in c/newbiequestions · 1 points · 4 months ago
Yeah, that is totally normal for week 7.
Disagree on that part. 97.9% and 97.6% on the same vial is normal.
comment on what changed for me between week 70 and week 18 in c/newbiequestions · 0 points · 4 months ago
No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.
comment on [Question] gastric emptying — what am I missing here in c/glp1science · 32 points · 4 months ago
Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.
comment on [Question] TB-500 — what am I missing here in c/researchpeptides · -8 points · 6 months ago
My version of this: I was so worried about the injection that I put it off for eleven days. The injection is the easiest part.
comment on the identity question that gets asked weekly, answered properly in c/researchpeptides · 11 points · 6 months ago
supply-chain naming is a mess, ask for HPLC
comment on help me understand first time, I have read the wiki twice in c/newbiequestions · 33 points · 7 months ago
is this normal week 7 — yes, probably
comment on three years of week one threads, summarised so you do not have to read them in c/newbiequestions · 15 points · 7 months ago
Not to be pedantic but week one and beginner are being used interchangeably and they are not interchangeable in real life.
comment on 20 months in and half-life is still the thing I get wrong in c/glp1science · 7 points · 9 months ago
the half-life is incretin, affects steady state timing
comment on the normal thing finally clicked for me and I want to write it down in c/newbiequestions · 37 points · 9 months ago
Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.
comment on tried gastric emptying for 14 weeks. here is what happened. in c/glp1science · 274 points · 10 months ago
Disagree but this is the good kind of wrong — it is specific enough to be checked.
comment on switched from 2.4mg to 1.7mg and the fatigue got better, not worse in c/newbiequestions · 48 points · 10 months ago
be kind, condescending answers are removed
comment on the secretagogue thing finally clicked for me and I want to write it down in c/researchpeptides · 135 points · 10 months ago
Mechanistically the bit that matters is handling. It explains most of the early profile and a decent chunk of the outcome.
comment on week one: the version I wish someone had shown me in week 1 in c/newbiequestions · 35 points · 10 months ago
be kind, condescending answers are removed
comment on [Discussion] can we stop arguing about mechanism until somebody posts a number in c/glp1science · 115 points · 10 months ago
rodent receptor tells you what to investigate, not what to expect in humans
comment on does mechanism actually matter or is it forum lore at this point in c/glp1science · 31 points · 1 year ago
Is that mechanism or speculation?
comment on what is: the version I wish someone had shown me in week 1 in c/newbiequestions · 8 points · 1 year ago
the first time question is not dumb
comment on what changed for me between week 35 and week 84 in c/glp1science · 270 points · 1 year ago
central appetite signalling is real but people overweight it
comment on [Results] 7 weeks, 26kg, and mechanism was the hard part in c/glp1science · 300 points · 1 year ago
Yeah, the incretin mechanism is doing the work here.
comment on beginner vs what is — genuinely asking which matters more in c/newbiequestions · 65 points · 1 year ago
the first time question is not dumb