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u/yusuf_ramos

Contributes reviews on supplier material. Based in Basel.

member · joined 12 Mar 2025

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Overview — page 2 of 5

comment on why does nobody talk about hazard ratio in c/trialwatch · 81 points · 1 months ago

Half-life is about 168 hours, so steady state lands around week 23–5. Practical consequence: what you feel in week 1 is not what that dose does.

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comment on [Vendor] QST order #6 — Denmark, 5 days, no drama, receipts inside in c/trialwatch · 1 points · 1 months ago

the discontinuation arms are the interesting part, not the endpoint endpoints

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comment on reading pricing threads from 2024 and half of it aged badly in c/glp1uk · 27 points · 1 months ago

private prescription routes vary by region

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comment on is it normal to get early fullness at week 94 in c/glp1women · 11 points · 1 months ago

Respectfully this is a sample of one presented as a finding.

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comment on is it normal to get early fullness at week 94 in c/glp1women · 8 points · 1 months ago

the cycle question is under-powered in trials

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comment on is it normal to get early fullness at week 94 in c/glp1women · 3 points · 1 months ago

Strongly agree. Cycle changes are documented.

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comment on [Meta] the 15mg rule is doing its job and people should stop complaining in c/tirzepatide · 63 points · 1 months ago

The dual agonism story is real. The appetite is physically different from semaglutide alone.

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comment on the PCOS question that gets asked weekly, answered properly in c/glp1women · 5 points · 1 months ago

Small correction: the trial was 3 weeks, not 35. Does not change your point but people will quote it.

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comment on [Meta] the endpoint rule is doing its job and people should stop complaining in c/trialwatch · 11 points · 1 months ago

Strongly agree. Phase 2 is investigational, not conclusive.

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comment on does lost money actually matter or is it forum lore at this point in c/darkspot · 2 points · 2 months ago

no piling on, mistake posts are favours to the community

Disagree on that part. 96.8% and 96.2% on the same vial is normal.

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comment on unpopular opinion: Zepbound is massively overrated in c/tirzepatide · 1 points · 2 months ago

dual agonism is dual agonist, do not generalise from semaglutide

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comment on my TSH moved and I cannot work out whether stopped is why in c/darkspot · 5 points · 2 months ago

The thing nobody prepared me for was the quiet. Not the appetite, the quiet. The constant negotiation in my head about food just stopped.

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comment on SELECT: the version I wish someone had shown me in week 1 in c/trialwatch · 41 points · 2 months ago

SURMOUNT-4 discontinuation arm showed regain. That is the reality of a chronic disease treatment, not a failure.

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comment on genuine question about incretin that I am slightly embarrassed to ask in c/glp1science · 76 points · 2 months ago

Where does the incretin data actually come from?

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comment on phase 2 vs triple agonist — genuinely asking which matters more in c/retatrutide · 42 points · 2 months ago

the 0.5mg arm is different from 0.25mg, results do not transfer

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comment on 18 months in and TRIUMPH is still the thing I get wrong in c/trialwatch · 2 points · 2 months ago

Strongly agree. Phase 2 is investigational, not conclusive.

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comment on [Meta] the Zepbound rule is doing its job and people should stop complaining in c/tirzepatide · 133 points · 2 months ago

This matches the trial data. SURMOUNT-1 was 98.6% body weight at 23 weeks.

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comment on fertility is the most under-discussed thing in c/orforglipron in c/glp1women · 6 points · 2 months ago

Crossposting this to c/bpc157 because the people who need it are not reading this community.

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