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c/glp1women·posted 1 months ago by u/tared_twice

is it normal to get early fullness at week 94

Results Clean Column ×9 Slow Clap ×2

Something I noticed reading old threads that I have not seen said out loud.

The advice on perimenopause in this community changed substantially around the start of last year, and nobody went back and updated the older posts. So depending on which thread the search engine hands you, you get two contradictory answers with the same confidence.

I have listed what I think the current consensus is below. Correct me — that is the point of posting it.

4,121 up / 3,048 down57% upvoted65 commentsid 164kb416 Jun 2026

65 comments

27 in this archive, depth 4

best — the order this archive was captured in

u/coa_forgery_watch113 points·1 months ago
fair enough
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u/tared_twiceOP47 points·1 months ago

Strongly agree. Cycle changes are documented.

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u/low_appetite_lisaMOD60 points·1 months ago

Tracking number removed. It identifies both ends of a shipment.

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u/jarno_karlsen29 points·1 months ago

Strongly agree. Cycle changes are documented.

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u/elodie_kuipers87 points·1 months ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/micro_bump_mick111 points·1 months ago

fertility signal is there but unclear

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u/hair_shed_hannah132 points·1 months ago·edited

Slight fix: the number was 98.3, not 98.4. Decimal point, but a fairly consequential one.

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u/pavel_nkemelu49 points·1 months ago

PCOS and insulin resistance

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u/yusuf_ramos11 points·1 months ago

Respectfully this is a sample of one presented as a finding.

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u/sulphur_burps_sue13 points·1 months ago

the cycle question is under-powered in trials

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[deleted]5 points·1 months ago

[deleted]

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u/rina_sobczak6 points·1 months ago

fertility signal is there but unclear

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u/jonas_cardoso2 points·1 months ago

[deleted]

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/sanne_novak27 points·1 months ago

cycle changes are real and under-researched

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u/ewan_tulloch6 points·1 months ago

I am going to push back on this slightly.

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u/tared_twiceOP3 points·1 months ago

Has anyone actually got this in writing, or is it forum lore at this point?

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u/aleksi_grimaldi23 points·1 months ago

contraception interaction claims need citation

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u/nayeli_iyer13 points·1 months ago

Second this question. I have wondered about contraception for 18 months and never seen a straight answer.

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u/kaia_fonseca8 points·1 months ago

pregnancy and trying-to-conceive get clinician pointer, not community advice

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u/emil_marchand2 points·1 months ago

the trials mostly studied men, perimenopause skipped

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u/tared_twiceOP3 points·1 months ago

Stalled for 14 weeks, changed nothing, and it started moving again on week 3.

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u/tared_twice9 points·1 months ago

Slight fix: the number was 96.8, not 94.2. Decimal point, but a fairly consequential one.

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u/yusuf_ramos8 points·1 months ago

the cycle question is under-powered in trials

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u/reads_the_wiki16 points·1 months ago

Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.

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u/elodie_yilmaz11 points·1 months ago

Yeah, PCOS is under-researched.

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u/yusuf_ramos3 points·1 months ago

Strongly agree. Cycle changes are documented.

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u/hair_shed_hannah2 points·1 months ago

You have restated the marketing copy. What is the actual substance here.

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About c/glp1women

The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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