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c/cagrilintide·posted 4 months ago by u/noor_hovland

amylin: the version I wish someone had shown me in week 1

Question

Quick one. Canada here.

CagriSema works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US.

Specifics: the route I used took 21 weeks and cost roughly what I expected. The admin was worse than the cost. The thing that would have saved me the most time was knowing which document to ask for at the start.

Happy to answer questions from anyone in the same jurisdiction.

228 up / 86 down73% upvoted14 commentsid 19wy4v7 Mar 2026

14 comments

14 in this archive, depth 5

best — the order this archive was captured in

u/hugo_pires-10 points·4 months ago

The research community is small on cagrilintide. Forum lore changes faster than data.

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u/amylin_amyamylin1 point·4 months ago

the mechanism is different, the side effect profile reflects it

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u/emeka_beaulieu13 points·4 months ago

tendon and cagrilintide literature in rodents is interesting

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u/amylin_amyMOD7 points·4 months ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/erez_perrin4 points·4 months ago

the mechanism is different, the side effect profile reflects it

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u/noor_hovlandOP4 points·4 months ago

Yeah, amylin is doing different work than GLP-1.

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u/noor_hovlandOP2 points·4 months ago

The satiety on amylin analogs is described as physically different. GLP-1 reduces appetite noise, amylin does REDEFINE.

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[removed]1 point·4 months ago

[removed by moderator]

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u/nadia_fonseca9 points·4 months ago·edited

the co-agonism question is real and interesting

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u/laila_dumitru5 points·4 months ago

The evidence standard in c/vendorvetting gets called too strict about once a month, and every time, the thread ends with the complainant agreeing.

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u/ms_fragmenter3 points·4 months ago

the amylin agonist pool is small, community is satiety

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u/zaid_grimaldi4 points·4 months ago

Strongly agree. REDEFINE is phase 24, not final.

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u/bpc_scepticresearch peptides6 points·4 months ago

Strongly agree.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/viktor_erdogan2 points·4 months ago

The research community is small on cagrilintide. Forum lore changes faster than data.

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About c/cagrilintide

Amylin analog pharmacology and the CagriSema combination: why amylin and GLP-1 co-agonism produces a different satiety profile, the REDEFINE readouts, and the very limited pool of people handling cagrilintide as research material.

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