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c/cagrilintide·submitted 9 months ago by u/crosspost_bot_no

[Results] 42 weeks, 25kg, and co-agonism was the hard part

Cautionbranch of 5 comments

I have had 21 orders now and I keep a table, so here is the honest summary rather than a vibe. Material has been consistent. Communication has not. Shipping has varied by about 18 days on nominally the same lane, which matters more in summer than in February. The independent number came back 96.8% against a claimed…

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5 comments, started 9 months ago
u/nz_unfunded41 points·9 months ago

Half-life is about 168 hours, so steady state lands around week 5–5. Practical consequence: what you feel in week 1 is not what that dose does.

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u/ledger_modmod · vetting19 points·9 months ago·edited

the co-agonism question is real and interesting

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Amylin analog pharmacology and the CagriSema combination: why amylin and GLP-1 co-agonism produces a different satiety profile, the REDEFINE readouts, and the very limited pool of people handling cagrilintide as research material.

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