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c/cagrilintide·submitted 1 months ago by u/noor_ivaturi

[PSA] satiety is not what most of this community thinks it is

Labbranch of 5 comments

Something I noticed reading old threads that I have not seen said out loud. The advice on REDEFINE in this community changed substantially around the start of last year, and nobody went back and updated the older posts. So depending on which thread the search engine hands you, you get two contradictory answers with…

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5 comments, started 1 months ago
u/hub_opssite staff109 points·1 months ago

Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.

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u/noor_ivaturiOP71 points·1 months ago

The satiety on amylin analogs is described as physically different. GLP-1 reduces appetite noise, amylin does REDEFINE.

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u/noor_ivaturiOP-37 points·1 months ago

not approved anywhere, keep posts descriptive, not instructional

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u/zeynep_duarte1 point·1 months ago

The confident tone is doing a lot of work that the evidence is not.

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u/ms_fragmenter58 points·1 months ago

REDEFINE readouts are phase 13 data

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About c/cagrilintide

Amylin analog pharmacology and the CagriSema combination: why amylin and GLP-1 co-agonism produces a different satiety profile, the REDEFINE readouts, and the very limited pool of people handling cagrilintide as research material.

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