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c/cagrilintide·submitted 1 months ago by u/sulphur_burps_sue

stalled for 5 weeks at 2.5mg and I refuse to panic this time

Labbranch of 6 comments

Long-ish post, sorry. tl;dr at the bottom. I have been tracking cagrilintide against triglycerides for 29 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here. Caveats up front: one person, one…

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6 comments, started 1 months ago
u/elin_lundgren39 points·1 months ago

amylin is not a GLP-1, posts conflating them get corrected

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u/clara_weiss24 points·1 months ago

REDEFINE which arm?

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u/ledger_modMOD14 points·1 months ago

This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.

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u/blunt_coldbox22 points·1 months ago

the co-agonism question is real and interesting

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u/emeka_chowdhury8 points·1 months ago·edited

This is correct. The co-agonism is real.

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u/sulphur_burps_sueOP9 points·1 months ago

the mechanism is different, the side effect profile reflects it

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Amylin analog pharmacology and the CagriSema combination: why amylin and GLP-1 co-agonism produces a different satiety profile, the REDEFINE readouts, and the very limited pool of people handling cagrilintide as research material.

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