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c/coa·submitted 1 months ago by u/anya_moreau

anyone else notice water content kicking in around week 50

Discussionbranch of 12 comments

Trying to settle this properly because the thread from last year went in circles. The claim: certificate of analysis matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 24 months without either producing anything. What would actually settle it is 27 people…

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12 comments, started 1 months ago
u/coa_collectorMOD176 points·1 months ago

This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.

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u/purity_pedantanalytical134 points·1 months ago

no "is this good?" without saying what the compound and claimed purity are

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u/bastian_moreau47 points·1 months ago

area% is not mass%, and here is exactly why it matters

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u/dario_vermeulen90 points·1 months ago·edited

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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u/india_generic_g67 points·1 months ago

no "is this good?" without saying what the compound and claimed purity are

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/kavya_verhoeven55 points·1 months ago

the batch number or it did not happen

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u/katrin_girard141 points·1 months ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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u/tomas_lehtinen36 points·1 months ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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[deleted]117 points·1 months ago

[deleted]

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u/anya_moreauOP89 points·1 months ago

post the whole document, not the headline number

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u/anya_moreauOP70 points·1 months ago

post the whole document, not the headline number

Yes, exactly this, and it is the bit that took me 47 weeks to accept.

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u/aurel_boateng22 points·1 months ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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About c/coa

How to read a certificate of analysis and what it does and does not tell you. Area% versus mass%, identity versus quantity, water content, related substances, acetate counterions, and the difference between a vendor-supplied COA and an independent test on the vial you actually received.

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