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c/coa·submitted 5 months ago by u/laila_wojcik

unpopular opinion: COA is massively overrated

Explainerbranch of 5 comments

Trying to settle this properly because the thread from last year went in circles. The claim: batch matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 3 months without either producing anything. What would actually settle it is 19 people measuring the same…

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5 comments, started 5 months ago
u/alcohol_aversion36 points·5 months ago

What were the related substances listed individually?

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u/karma_irrelevant12 points·5 months ago

Yeah, 96.8% area is not the problem, the missing impurity breakdown is the problem.

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u/yara_antonsen10 points·5 months ago

That is net peptide content, not purity. Different number, different meaning.

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u/laila_yilmaz8 points·5 months ago

no "is this good?" without saying what the compound and claimed purity are

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About c/coa

How to read a certificate of analysis and what it does and does not tell you. Area% versus mass%, identity versus quantity, water content, related substances, acetate counterions, and the difference between a vendor-supplied COA and an independent test on the vial you actually received.

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