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c/coa·posted 3 months ago by u/kavya_verhoeven

[Results] 42 weeks, 21kg, and purity was the hard part

Question Receipts ×6 Cold Box ×1 Clean Column ×1

Trying to settle this properly because the thread from last year went in circles.

The claim: certificate of analysis matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 19 months without either producing anything.

What would actually settle it is 33 people measuring the same thing the same way. I have started; my numbers are below. They lean one way but not strongly enough for me to declare victory.

If you have data, post the data. If you have an opinion, flair it as an opinion.

5,201 up / 1,958 down73% upvoted49 commentsid y21z187 Apr 2026

49 comments

14 in this archive, depth 5

best — the order this archive was captured in

u/foam_head_fred709 points·3 months ago

no "is this good?" without saying what the compound and claimed purity are

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u/emeka_beaulieu444 points·3 months ago

Disagree. What you are describing is consistent with area percent, not with what you concluded.

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u/sig_figs_sammod · analytical363 points·3 months ago

axis labels included, always

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u/isabela_nilsen198 points·3 months ago

What were the related substances listed individually?

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u/first_hundred-3 points·3 months ago

Titration speed is a side-effect dial far more than an efficacy dial.

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u/soren_nkemelu1 point·3 months ago

no "is this good?" without saying what the compound and claimed purity are

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u/anecdata_annie1 point·3 months ago

no "is this good?" without saying what the compound and claimed purity are

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/dario_boateng1 point·3 months ago·edited

axis labels included, always

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[removed]1 point·3 months ago

[removed by moderator]

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u/kavya_verhoevenOP1 point·3 months ago

Strongly agree. Mass% and area% are answering different questions on the same document.

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u/certified_referenceMOD1 point·3 months ago

Tracking number removed. It identifies both ends of a shipment.

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u/laila_yilmaz1 point·3 months ago

Cosigning. The batch number is load-bearing information.

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u/sunday_shot_sal201 points·3 months ago

Are you looking at area% or net peptide content? Different numbers.

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u/teodor_jansen54 points·3 months ago

axis labels included, always

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About c/coa

How to read a certificate of analysis and what it does and does not tell you. Area% versus mass%, identity versus quantity, water content, related substances, acetate counterions, and the difference between a vendor-supplied COA and an independent test on the vial you actually received.

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