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813

am I the only one who found cold chain harder than the injections

Question Long Haul ×4

Week 84 update. 25kg down from the start, reflux basically gone since about week 29.

Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with reflux.

The part that surprised me is how much of this is admin. Ordering, storing, logging, remembering. Nobody mentions that the hard bit is not the drug, it is the routine.

Happy to answer anything. Please do not ask me what dose you should be on.

1,211 up / 398 down75% upvoted58 commentsid p95qmb23 Nov 2024

58 comments

18 in this archive, depth 4

best — the order this archive was captured in

u/careful_gradient_again74 points·1 year ago

stability after excursion is not zero, it is dose-dependent

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u/coldchain_karenMOD56 points·1 year ago

Removed a chain here. The rule is one line long and it is not negotiable.

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u/search_before_post21 points·1 year ago

Small correction: the trial was 11 weeks, not 13. Does not change your point but people will quote it.

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u/priya_guerrero45 points·1 year ago

no tracking numbers, no full addresses, no label photos — instant removal

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u/ms_fragmenter34 points·1 year ago

Yeah, data logger is the only acceptable proof.

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u/intent_to_treat31 points·1 year ago

The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.

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u/isabela_nilsen8 points·1 year ago

lyophilised powder is far more forgiving than reconstituted solution

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u/milan_mensah2 points·1 year ago

data logger is the standard, gut feeling is not

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u/noor_cardoso19 points·1 year ago

the logger trace is the data that matters, not the packaging promises

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u/marta_ilunga9 points·1 year ago

time-at-temperature integral is the dose, not just peak temperature

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u/bruno_dumitru16 points·1 year ago

Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.

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u/analog_alphabet9 points·1 year ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/marit_laurent3 points·1 year ago·edited

customs clearance often breaks the cold chain, factor that in

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u/tidy_vialdrawer_watch28OP2 points·1 year ago

Which carrier and route?

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About c/coldchain

Temperature and stability in the real world: what an excursion actually costs you, why lyophilised powder is far more forgiving than reconstituted solution, how to read a logger CSV, and how to photograph a failed shipment so the conversation with the vendor is short.

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