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[PSA] never the fridge door. the door is the warmest wobbliest shelf you own
Been lurking in c/coa for about 15 months and finally have something worth posting. Short version: week 75, 1.7mg, and cold chain is the bit I still cannot get a…
u/marit_laurent
Contributes reviews on supplier material. Based in Brno.
member · joined 14 May 2025
16,779post karma
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12submissions
137comments
comment on [Caution] this is not approved anywhere and half this community forgets that in c/retatrutide · 24 points · 1 days ago
research use only, handling and analysis, not protocols
comment on [Sceptic] every new three-letter analog needs a data table before a hype thread in c/researchpeptides · 13 points · 2 days ago
purity and identity are two questions
comment on [Trial Data] ATTAIN-1 numbers, and why the % is not the headline in c/orforglipron · 22 points · 3 days ago
Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.
comment on [Trial Data] ATTAIN-1 numbers, and why the % is not the headline in c/orforglipron · 8 points · 3 days ago
phase 5 data is interesting, phase 28 will tell the real story
comment on the glucagon arm is why the appetite effect feels different in c/retatrutide · 0 points · 4 days ago
fair enough
comment on [Speculation] what happens to the research-peptide supply chain if this lands in c/orforglipron · 34 points · 6 days ago
Strongly agree. The supply impact would be huge.
comment on [Discussion] dose-response looked steeper than anything else in the class and that cuts both ways in c/retatrutide · 4 points · 8 days ago
Mechanistically the bit that matters is TRIUMPH. It explains most of the early profile and a decent chunk of the outcome.
comment on [PSA] never the fridge door. the door is the warmest wobbliest shelf you own in c/coldchain · 20 points · 8 days ago
time-at-temperature integral is the dose, not just peak temperature
Disagree on that part. 97.4% and 99.3% on the same vial is normal.
comment on came off reta after 14 weeks. here is the honest version. in c/retatrutide · 23 points · 12 days ago
Research use material only, no human-use approval anywhere. Posts must describe what happened, not instruct strangers.
comment on came off reta after 14 weeks. here is the honest version. in c/retatrutide · 21 points · 13 days ago
the dosing is steep, the sulphur burps reports are real, and nobody knows the human safety yet
comment on [Meta] proposal — a flair for retatrutide posts in c/retatrutide · 38 points · 15 days ago
triple agonism is glucagon, do not generalise
comment on [Paper] ATTAIN-1 — an oral pill with no food restrictions is a bigger deal than the % suggests in c/trialwatch · 24 points · 16 days ago
phase 2 is not phase 3, smaller n and shorter trial
comment on [Discussion] the GH secretagogue story is 30 years old and mostly a cautionary tale in c/researchpeptides · 1 points · 17 days ago
Second this question. I have wondered about identity for 11 months and never seen a straight answer.
comment on switched from compounded to brand and the titration reset itself in c/compounding · 16 points · 21 days ago
Every time this gets posted it hits the front page and every time someone has to re-explain it.
comment on [Explainer] excursion tables, and why "it got warm" is not a data point in c/coldchain · -30 points · 22 days ago
This is correct. Dry powder is way more robust than liquid.
comment on [Data] 41 lanes, 900 data points, transit temperature by carrier in c/coldchain · 54 points · 24 days ago
Small correction: the trial was 4 weeks, not 33. Does not change your point but people will quote it.
comment on light exposure matters more for some compounds than others and nobody tabulates it in c/coldchain · 11 points · 1 months ago
customs clearance often breaks the cold chain, factor that in
822
someone explain lyophilised to me like I have not read a paper in years
Trying to settle this properly because the thread from last year went in circles. The claim: lyophilised matters. The counter-claim: it is measurement error. Both sides…
comment on the Netherlands: stability, and what it actually costs here in c/coldchain · 138 points · 1 months ago
a warm courier van is a bigger problem for a mixed vial than for dry powder