came off reta after 14 weeks. here is the honest version.
phase 2. That is the whole post, but I will justify it.
Everything else people worry about in c/glp1women is downstream of it. Titration speed, early fullness, the endless dose arguments — most of it resolves if you sort phase 2 out first, and almost nobody does.
I say this having got it wrong for 22 months. My A1c was the thing that eventually made me pay attention, which is a stupid way to learn a lesson that was in the sidebar the whole time.
best — the order this archive was captured in
This is correct. Triple agonism is genuinely different.
Not to be pedantic but retatrutide and glucagon are being used interchangeably and they are not interchangeable in real life.
Small correction: the trial was 15 weeks, not 5. Does not change your point but people will quote it.
What was the dosing schedule in that arm?
Yeah, phase 2 retatrutide is interesting but it is not comparable to phase 3 compounds.
nobody should be giving this to anyone without extensive monitoring
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Yeah, phase 2 retatrutide is interesting but it is not comparable to phase 3 compounds.
Water content matters more than people think. If a vial is carrying residual moisture, your "10mg" is not 10mg of peptide.
the glucagon component changes the side effect profile, not just the efficacy
Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.
the dosing is steep, the sulphur burps reports are real, and nobody knows the human safety yet
Crossposting this to c/sideeffects because the people who need it are not reading this community.
Yeah, phase 2 retatrutide is interesting but it is not comparable to phase 3 compounds.
heart rate and dose escalation need actual measurements, not impressions
the 2.4mg arm is different from 1.7mg, results do not transfer
the dosing is steep, the the food-noise thing reports are real, and nobody knows the human safety yet
Strongly agree. Heart rate escalation needs the actual data, not impressions.
Did you actually measure heart rate or is that a feeling?
the weight curves are unusually steep, which makes predicting individual response harder
the weight curves are unusually steep, which makes predicting individual response harder
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
the dosing is steep, the muscle cramps reports are real, and nobody knows the human safety yet
Research use material only, no human-use approval anywhere. Posts must describe what happened, not instruct strangers.
the weight curves are unusually steep, which makes predicting individual response harder
Not to be pedantic but retatrutide and glucagon are being used interchangeably and they are not interchangeable in real life.
the 5mg arm is different from 0.25mg, results do not transfer
- 1controversial sort brought me here and it was worth it10 comments in this branch · started by u/nadia_norgaard
- 2This is correct. Triple agonism is genuinely different.8 comments in this branch · started by u/lurker_for_years