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Single comment threadYou are looking at one branch of came off reta after 14 weeks. here is the honest version. — 56 comments in the full submission. View in context.
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c/retatrutide·submitted 13 days ago by u/cormac_roos

came off reta after 14 weeks. here is the honest version.

Trial Databranch of 10 comments

phase 2. That is the whole post, but I will justify it. Everything else people worry about in c/glp1women is downstream of it. Titration speed, early fullness, the endless dose arguments — most of it resolves if you sort phase 2 out first, and almost nobody does. I say this having got it wrong for 22 months. My A1c…

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This branch

10 comments, started 12 days ago
u/nadia_norgaard47 points·12 days ago
controversial sort brought me here and it was worth it
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u/nausea_notesside effects36 points·11 days ago

Strongly agree. Heart rate escalation needs the actual data, not impressions.

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u/anya_moreau31 points·11 days ago

Did you actually measure heart rate or is that a feeling?

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u/heart_rate_bump24 points·11 days ago

the weight curves are unusually steep, which makes predicting individual response harder

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u/halima_mbeki18 points·11 days ago

the weight curves are unusually steep, which makes predicting individual response harder

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/yara_lindholm5 points·11 days ago·edited

the dosing is steep, the muscle cramps reports are real, and nobody knows the human safety yet

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u/marit_laurent23 points·12 days ago

Research use material only, no human-use approval anywhere. Posts must describe what happened, not instruct strangers.

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u/vito_beaulieu8 points·11 days ago·edited

the weight curves are unusually steep, which makes predicting individual response harder

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u/nikhil_asante7 points·11 days ago·edited

Not to be pedantic but retatrutide and glucagon are being used interchangeably and they are not interchangeable in real life.

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u/matias_falk3 points·11 days ago

the 5mg arm is different from 0.25mg, results do not transfer

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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c/retatrutide rules
  1. Retatrutide is not approved anywhere for human use. Posts must not read as usage instructions.
  2. Phase 2 numbers are not maintenance numbers. Cite the trial and the dose arm.
  3. Heart-rate and dose-escalation reports need actual measurements, not impressions.
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