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c/compounding·posted 1 year ago by u/marit_laurent

switched from 12.5mg to 0.5mg and the fatigue got better, not worse

Regulatory

Trying to settle this properly because the thread from last year went in circles.

The claim: compounding matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 10 months without either producing anything.

What would actually settle it is 3 people measuring the same thing the same way. I have started; my numbers are below. They lean one way but not strongly enough for me to declare victory.

If you have data, post the data. If you have an opinion, flair it as an opinion.

225 up / 234 down50% upvoted7 commentsid kkt96031 May 2025

7 comments

7 in this archive, depth 3

best — the order this archive was captured in

u/chidi_demir6 points·1 year ago

Every time this gets posted it hits the front page and every time someone has to re-explain it.

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u/honest_syringe3 points·1 year ago

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

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u/formulary_fighterMOD2 points·1 year ago

Tracking number removed. It identifies both ends of a shipment.

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u/marit_laurentOP1 point·1 year ago

the 503A/503B distinction is load-bearing, do not blur it

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u/ilias_cabrera2 points·1 year ago

Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.

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u/pavel_kravchenko2 points·1 year ago

Asked 5 compounders about API source. One told me, one dodged, one said they cannot say. The answer is the signal.

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u/yusuf_kirchner1 point·1 year ago

Yeah, 503A and 503B are different regulatory animals.

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About c/compounding

Compounded GLP-1s as a supply route: the 503A/503B distinction, the shortage-list mechanics that made compounding legal and then didn't, state board rules, telehealth prescriber models, and what a compounding pharmacy will and will not tell you about its API source.

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