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c/compounding·posted 2 months ago by u/discount_math_dm

Spain: 503B, and what it actually costs here

Explainer Long Haul ×9

Been lurking in c/maintenancephase for about 11 months and finally have something worth posting.

Short version: week 39, 10mg, and 503A is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 35 threads, and the answers split roughly down the middle.

What I actually want to know is whether the people saying it does not matter have measured it, or whether it is just repeated confidently. Happy to be told I am overthinking this — I probably am — but I would rather overthink it now than at week 45.

821 up / 183 down82% upvoted31 commentsid kkwenz28 May 2026

31 comments

24 in this archive, depth 5

best — the order this archive was captured in

u/rafael_ostergaard51 points·2 months ago

Which state? Rules vary.

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u/discount_math_dmOP22 points·2 months ago

API transparency is the question that separates good compounders from sketchy ones

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u/discount_math_dmOP60 points·2 months ago

Are we talking 503A or 503B?

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u/yusuf_kirchner74 points·2 months ago

telehealth prescriber models exist, pricing differs by state

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u/ayesha_radich36 points·2 months ago

Yeah, 503A and 503B are different regulatory animals.

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u/honest_syringe21 points·2 months ago

What is the actual shortage list status right now?

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u/receptor_bias_rick16 points·2 months ago

Which state? Rules vary.

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u/jonas_eriksen11 points·2 months ago

telehealth costs API source plus compounding markup, total varies

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u/ayesha_radich7 points·2 months ago

The 503A pharmacy I used lost their shortage list eligibility. Same day, compounding became illegal. Rules are real.

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[removed]3 points·2 months ago

[removed by moderator]

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u/slow_logbook1 point·2 months ago

telehealth prescriber models exist, pricing differs by state

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u/prior_auth_painappeals-28 points·2 months ago

telehealth prescriber models exist, pricing differs by state

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/ignacio_vanhecke1 point·2 months ago·edited

telehealth costs API source plus compounding markup, total varies

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u/chidi_demir14 points·2 months ago

shortage list status is state board, check the actual list

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u/marit_laurent10 points·2 months ago

Not convinced. The evidence does not support that reading.

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u/kavya_kravchenko3 points·2 months ago

the shortage list is temporary, it ends and compounding becomes illegal again

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u/tb500_tangent4 points·2 months ago

Not convinced.

Yes, exactly this, and it is the bit that took me 14 weeks to accept.

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u/yannick_barros4 points·2 months ago

Yeah, 503A and 503B are different regulatory animals.

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u/naomi_erdogan7 points·2 months ago

The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.

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u/prior_auth_painMOD3 points·2 months ago

Removed a chain here. The rule is one line long and it is not negotiable.

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u/discount_math_dmOP1 point·2 months ago

Asked 20 compounders about API source. One told me, one dodged, one said they cannot say. The answer is the signal.

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u/rania_diallo6 points·2 months ago

state board rules differ, say which state

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About c/compounding

Compounded GLP-1s as a supply route: the 503A/503B distinction, the shortage-list mechanics that made compounding legal and then didn't, state board rules, telehealth prescriber models, and what a compounding pharmacy will and will not tell you about its API source.

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