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498

503B — 15 things I got wrong before I got it right

Question Cold Box ×6

Week 86 update. 7kg down from the start, reflux basically gone since about week 31.

Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with reflux.

The part that surprised me is how much of this is admin. Ordering, storing, logging, remembering. Nobody mentions that the hard bit is not the drug, it is the routine.

Happy to answer anything. Please do not ask me what dose you should be on.

773 up / 275 down74% upvoted30 commentsid kusuuz13 Jun 2025

30 comments

21 in this archive, depth 5

best — the order this archive was captured in

u/ferran_mensah108 points·1 year ago·edited

telehealth prescriber models exist, pricing differs by state

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u/eu_apotheke_a68 points·1 year ago

I am going to push back on this slightly.

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u/burned_once_twice46 points·1 year ago·edited

telehealth costs state board plus compounding markup, total varies

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u/blunt_coldbox_notesOP0 points·1 year ago

Strongly agree. API source transparency matters.

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u/bruno_dumitru-4 points·1 year ago

regulatory claims need a citation to the actual rule, not interpretation

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u/blunt_coldbox_notesOP1 point·1 year ago

The telehealth + compounding combo cost shortage list plus 17% markup. Not cheap but covered by insurance depending on state.

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u/fatima_kowalski61 points·1 year ago

Titration speed is a side-effect dial far more than an efficacy dial.

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[removed]45 points·1 year ago

[removed by moderator]

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u/emeka_chowdhury39 points·1 year ago

Not to be pedantic but state board and 503A are being used interchangeably and they are not interchangeable in real life.

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u/cold_chromatogram3131 points·1 year ago

regulatory claims need a citation to the actual rule, not interpretation

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u/niels_roos25 points·1 year ago·edited

Strongly agree. API source transparency matters.

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u/blunt_coldbox_notesOP11 points·1 year ago

no pharmacy referral codes, naming is fine, recruiting is not

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u/stubborn_batchlist_pls42 points·1 year ago

telehealth prescriber models exist, pricing differs by state

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u/helga_vermeulen27 points·1 year ago

no pharmacy referral codes, naming is fine, recruiting is not

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u/ignacio_vanhecke9 points·1 year ago

Which state? Rules vary.

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u/prior_auth_painappeals9 points·1 year ago·edited

shortage list status is API source, check the actual list

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u/neha_krastev10 points·1 year ago

the shortage list is temporary, it ends and compounding becomes illegal again

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u/ilias_cabrera20 points·1 year ago

the 503A/503B distinction is load-bearing, do not blur it

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u/swirl_dont_shakereconstitution20 points·1 year ago

telehealth costs API source plus compounding markup, total varies

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u/marit_laurent15 points·1 year ago

the 503A/503B distinction is load-bearing, do not blur it

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u/incretin_ivypharmacology12 points·1 year ago

Did they tell you their API source or dodge the question?

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About c/compounding

Compounded GLP-1s as a supply route: the 503A/503B distinction, the shortage-list mechanics that made compounding legal and then didn't, state board rules, telehealth prescriber models, and what a compounding pharmacy will and will not tell you about its API source.

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