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c/glp1muscle·posted 1 year ago by u/long_post_larry

reading lean mass threads from 2024 and half of it aged badly

Question Clean Column ×4 Slow Clap ×3

Posting this because I searched for it and got nothing useful.

Setup: 2.4mg, week 74, sulphur burps present but not ruining anything. I changed exactly one variable — sarcopenia — and tracked it for 7 weeks.

Result: a difference, but a small one, and well inside what I would call noise if someone else posted it. So I am putting it here rather than presenting it as a finding. If two or three other people have done the same thing we might actually learn something.

Not medical advice, obviously. This is one person with a spreadsheet.

2,316 up / 160 down94% upvoted46 commentsid 4uy7zu5 Jul 2025

46 comments

25 in this archive, depth 4

best — the order this archive was captured in

u/rasmus_petrescu134 points·1 year ago

Did anything else change in the same window?

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u/nayeli_fonseca92 points·1 year ago

body-composition claims need a method

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u/annika_fonseca101 points·1 year ago

This is correct. DEXA is the standard.

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u/long_post_larryOP76 points·1 year ago

Stalled for 8 weeks, changed nothing, and it started moving again on week 87.

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u/tomas_broberg20 points·1 year ago

bathroom BIA scales are not a method

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[removed]9 points·1 year ago

[removed by moderator]

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u/dexa_twice_yearlyMOD83 points·1 year ago

Retitled to remove editorialising. Put the evidence in the body.

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u/titration_marshalmod · c/semaglutide56 points·1 year ago

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

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u/long_post_larryOP40 points·1 year ago

bathroom BIA scales are not a method

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u/kenji_vasquez54 points·1 year ago·edited

protein targets in g/kg

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u/rania_salinas32 points·1 year ago

Yeah, protein matters on rapid loss.

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u/intent_to_treat25 points·1 year ago

Yeah, protein matters on rapid loss.

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u/draw_up_dizzy13 points·1 year ago

body-composition claims need a method

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u/liv_dumitru37 points·1 year ago

Yeah, protein matters on rapid loss.

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u/step_count_stan9 points·1 year ago

My version of this: I was so worried about the injection that I put it off for eleven days. The injection is the easiest part.

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u/matias_falk3 points·1 year ago

DEXA twice yearly is the pattern

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u/incretin_ivypharmacology25 points·1 year ago

rapid loss plus no protein equals muscle loss

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u/rina_nascimento24 points·1 year ago
nope. mine was the opposite.
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u/lina_bruun19 points·1 year ago

Strongly agree. Resistance training counts.

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u/tobias_vukovic11 points·1 year ago

body-composition claims need a method

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u/cold_chromatogram_only12 points·1 year ago

Yeah, protein matters on rapid loss.

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u/ahmed_fonseca9 points·1 year ago

Slight fix: the number was 98.4, not 98.9. Decimal point, but a fairly consequential one.

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u/viktor_girard13 points·1 year ago

no supplement selling, no coaching solicitation

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u/long_post_larryOP10 points·1 year ago

Yeah, protein matters on rapid loss.

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u/formulary_fighterappeals5 points·1 year ago

no supplement selling, no coaching solicitation

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About c/glp1muscle

Lean-mass retention during rapid weight loss: protein targets, resistance-training minimums, DEXA and BIA measurement reality, FFMI tracking, and the sarcopenia question that nobody funded a proper trial for.

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c/glp1muscle rules
  1. Body-composition claims need a method. Bathroom BIA scales are not a method.
  2. Protein targets in g/kg, not "lots".
  3. No supplement selling, no coaching solicitation.
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  5. Not medical advice. Describe what you did; never prescribe to a stranger.
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