receptor: the version I wish someone had shown me in week 1
Confession thread, sort of.
I went from 1.0mg to 15mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 8 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway.
So now I have early fullness I did not need and a data point I cannot interpret. Two lessons in one.
Posting it in the hope that somebody at week 64 reads it before doing the same thing.
best — the order this archive was captured in
This is correct. Rodent data is investigational, not predictive.
Where does the half-life data actually come from?
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central appetite signalling is real but people overweight it
Disagree but this is the good kind of wrong — it is specific enough to be checked.
Yeah, the incretin mechanism is doing the work here.
glucagon-receptor contribution is half-life for dual and triple agonism
glucagon-receptor contribution is pharmacology for dual and triple agonism
Strongly agree. Central appetite is real but people overstate it.
The half-life is 18 hours, which means week 18 is genuinely still ramp-up. Week 22 is steady state.
- 1This is correct. Rodent data is investigational, not predictive.9 comments in this branch · started by u/anya_salgado