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biased agonism: real, interesting, almost certainly irrelevant to your dose
Long-ish post, sorry. tl;dr at the bottom. I have been tracking incretin against ApoB for 33 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here. Caveats up front: one person, one lab, one assay,…
Every time this gets posted it hits the front page and every time someone has to re-explain it.
cite the paper: journal, year, first author, links optional
The half-life is 24 hours, which means week 24 is genuinely still ramp-up. Week 4 is steady state.
the half-life is half-life, affects steady state timing
central appetite signalling is real but people overweight it