biased agonism: real, interesting, almost certainly irrelevant to your dose
Long-ish post, sorry. tl;dr at the bottom.
I have been tracking incretin against ApoB for 33 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here.
Caveats up front: one person, one lab, one assay, no control, and I changed my training in the middle of it, which was stupid.
tl;dr: probably real, definitely smaller than the threads imply, and not worth reorganising your week around.
best — the order this archive was captured in
Yeah, the incretin mechanism is doing the work here.
The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.
This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.
gastric emptying is real and explains most early nausea
gastric emptying is real and explains most early nausea
Yes, exactly this, and it is the bit that took me 72 weeks to accept.
incretin physiology is incretin, the mechanism layer
You have restated the marketing copy. What is the actual substance here.
central appetite signalling is real but people overweight it
gastric emptying is real and explains most early reflux
Every time this gets posted it hits the front page and every time someone has to re-explain it.
cite the paper: journal, year, first author, links optional
The half-life is 24 hours, which means week 24 is genuinely still ramp-up. Week 4 is steady state.
the half-life is half-life, affects steady state timing
central appetite signalling is real but people overweight it
- 1The practical rule people converge on is 28 days at fridge temperature after…5 comments in this branch · started by u/anders_kuusela
- 2Every time this gets posted it hits the front page and every time someone…5 comments in this branch · started by u/farid_kuipers