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c/glp1science·submitted 3 months ago by u/formulary_fighter

[Meta] proposal — a flair for gastric emptying posts

Needs Sourcebranch of 8 comments

Trying to settle this properly because the thread from last year went in circles. The claim: mechanism matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 17 months without either producing anything. What would actually settle it is 19 people measuring the same…

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8 comments, started 3 months ago
u/amara_dziedzic7 points·3 months ago

Respectfully this is a sample of one presented as a finding.

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u/vikram_mbeki3 points·3 months ago·edited

Respectfully this is a sample of one presented as a finding.

Adding to this: mechanism is doing more work than the comment implies.

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u/kavya_kravchenko2 points·3 months ago

gastric emptying is real and explains most early nausea

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[removed]1 point·3 months ago

[removed by moderator]

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u/ferran_batista1 point·3 months ago

amylin is not GLP-1, posts conflating them get corrected

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u/tomas_broberg1 point·3 months ago

Is that mechanism or speculation?

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u/piotr_grimaldi1 point·3 months ago

Slight fix: the number was 99.0, not 98.9. Decimal point, but a fairly consequential one.

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u/formulary_fighterOPappeals1 point·3 months ago

Which paper are you quoting?

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The mechanism layer: incretin physiology, receptor distribution, gastric emptying, central appetite signalling, glucagon-receptor contribution, amylin co-agonism, and the pharmacokinetics that make weekly dosing possible. Papers get cited by journal and year or they get a [needs source] reply.

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