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c/glp1science·submitted 2 months ago by u/gastric_emptying_g

help me understand appetite, I have read the wiki twice

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Posting this because I searched for it and got nothing useful. Setup: 15mg, week 71, sulphur burps present but not ruining anything. I changed exactly one variable — gastric emptying — and tracked it for 23 weeks. Result: a difference, but a small one, and well inside what I would call noise if someone else posted…

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4 comments, started 2 months ago
u/brigade_detector4 points·2 months ago

amylin is not GLP-1, posts conflating them get corrected

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u/georgi_chowdhury1 point·2 months ago

Not convinced. The evidence does not support that reading.

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u/noor_hovland1 point·2 months ago

receptor distribution matters, GLP-1 is not everywhere

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u/whois_wanda1 point·2 months ago

receptor distribution matters, GLP-1 is not everywhere

Adding to this: gastric emptying is doing more work than the comment implies.

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The mechanism layer: incretin physiology, receptor distribution, gastric emptying, central appetite signalling, glucagon-receptor contribution, amylin co-agonism, and the pharmacokinetics that make weekly dosing possible. Papers get cited by journal and year or they get a [needs source] reply.

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