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c/glp1women·submitted 1 year ago by u/santiago_marchetti

unpopular opinion: cycle is massively overrated

Fertilitybranch of 7 comments

Genuinely asking, not being difficult. Everyone in c/orforglipron repeats that insulin resistance is important. I believe it, but I have never seen anyone show why, and when I search I get 22 threads of people agreeing with each other. Is there a paper? Is there a measurement? Or is this one of those things that is…

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This branch

7 comments, started 1 year ago
u/georgi_haddad33 points·1 year ago

PCOS and insulin resistance

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u/zaid_grimaldi26 points·1 year ago

PCOS and insulin resistance

Disagree on that part. 98.7% and 99.0% on the same vial is normal.

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u/santiago_marchettiOP21 points·1 year ago

PCOS and insulin resistance Disagree on that part.

Disagree on that part. 93.7% and 99.3% on the same vial is normal.

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u/santiago_marchettiOP12 points·1 year ago

My version of this: I was so worried about the injection that I put it off for eleven days. The injection is the easiest part.

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u/kian_solberg7 points·1 year ago

the cycle question is under-powered in trials

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u/careful_gradient27 points·1 year ago

Yeah, insulin resistance is under-researched.

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u/greta_nilsen9 points·1 year ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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