unpopular opinion: cycle is massively overrated
Genuinely asking, not being difficult.
Everyone in c/orforglipron repeats that insulin resistance is important. I believe it, but I have never seen anyone show why, and when I search I get 22 threads of people agreeing with each other.
Is there a paper? Is there a measurement? Or is this one of those things that is true because it has been repeated since 2023?
I am not trying to be the "source?" guy. I would just like a source.
best — the order this archive was captured in
The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.
Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.
Did anything else change in the same window?
fertility signal is there but unclear
Second this question. I have wondered about cycle for 23 months and never seen a straight answer.
Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.
Slight fix: the number was 97.2, not 97.4. Decimal point, but a fairly consequential one.
Sweden here. Waited 21 months on a list, gave up, went private, and the total cost was roughly what I expected.
fertility signal is there but unclear
This is correct. PCOS is real.
[removed by moderator]
Genuine question — what concentration were you at?
the cycle tracking data matters, keep it private
hair-loss on contraception is real
You have restated the marketing copy. What is the actual substance here.
PCOS and insulin resistance
PCOS and insulin resistance
Disagree on that part. 98.7% and 99.0% on the same vial is normal.
PCOS and insulin resistance Disagree on that part.
Disagree on that part. 93.7% and 99.3% on the same vial is normal.
My version of this: I was so worried about the injection that I put it off for eleven days. The injection is the easiest part.
the cycle question is under-powered in trials
Yeah, insulin resistance is under-researched.
Sceptical. If this were true we would see it reflected in the data and we do not.
- 1PCOS and insulin resistance7 comments in this branch · started by u/georgi_haddad
- 2Did anything else change in the same window?6 comments in this branch · started by u/cold_chromatogram