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c/glp1women·submitted 1 months ago by u/mateusz_mensah

perimenopause — 8 things I got wrong before I got it right

Cautionbranch of 10 comments

Genuinely asking, not being difficult. Everyone in c/orforglipron repeats that insulin resistance is important. I believe it, but I have never seen anyone show why, and when I search I get 20 threads of people agreeing with each other. Is there a paper? Is there a measurement? Or is this one of those things that is…

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10 comments, started 1 months ago
u/ewan_zielinski0 points·1 months ago

I love that this community will spend 40 comments on a detail. That pedantry is why the numbers here matter.

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u/idris_kimani1 point·1 months ago

This is correct. PCOS is real.

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u/mateusz_mensahOP1 point·1 months ago

the cycle tracking data matters, keep it private

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u/georgi_haddad1 point·1 months ago·edited

fertility signal is there but unclear

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u/greta_nilsen1 point·1 months ago·edited

the cycle tracking data matters, keep it private

Adding to this: fertility is doing more work than the comment implies.

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u/kian_solberg0 points·1 months ago

contraception interaction claims need citation

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u/honest_syringe1 point·1 months ago

PCOS and insulin resistance

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u/forest_plot_fionastats1 point·1 months ago

hair-loss on contraception is real

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u/rui_only_ro1 point·1 months ago

the PCOS question is under-powered in trials

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u/viktor_laurent1 point·1 months ago

This is correct. PCOS is real.

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About c/glp1women

The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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