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c/glp1women·submitted 1 year ago by u/emeka_chowdhury

[Question] perimenopause — what am I missing here

Questionbranch of 9 comments

Genuinely asking, not being difficult. Everyone in c/darkspot repeats that insulin resistance is important. I believe it, but I have never seen anyone show why, and when I search I get 3 threads of people agreeing with each other. Is there a paper? Is there a measurement? Or is this one of those things that is true…

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9 comments, started 1 year ago
u/bastian_eriksen-2 points·1 year ago

the trials mostly studied men, perimenopause skipped

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u/joaquin_wojcik1 point·1 year ago·edited

PCOS and insulin resistance

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u/zaid_roos1 point·1 year ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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u/foam_head_fred1 point·1 year ago

PCOS and insulin resistance

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u/devils_advocate_d1 point·1 year ago

This is correct. PCOS is real.

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u/karim_restrepo1 point·1 year ago

I am going to push back on this slightly.

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u/rina_sobczak1 point·1 year ago·edited

hormonal contraception interactions are speculative

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u/emeka_chowdhury1 point·1 year ago·edited

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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