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c/glp1women·submitted 4 days ago by u/vitamin_d_void

[PCOS] insulin resistance, cycles, and the thing that finally worked

PCOSbranch of 6 comments

Trying to settle this properly because the thread from last year went in circles. The claim: cycle matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 14 months without either producing anything. What would actually settle it is 21 people measuring the same…

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6 comments, started 3 days ago
u/santiago_marchetti31 points·3 days ago

contraception interaction claims need citation

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u/elodie_yilmaz21 points·3 days ago

contraception interaction claims need citation

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/coa_forgery_watch11 points·3 days ago

hormonal contraception interactions are speculative

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u/vitamin_d_voidOP36 points·3 days ago

The thing nobody prepared me for was the quiet. Not the appetite, the quiet. The constant negotiation in my head about food just stopped.

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u/rina_sobczak28 points·3 days ago

The thing nobody prepared me for was the quiet.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/kian_solberg22 points·3 days ago·edited

hair-loss on cycle is real

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The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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