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c/glp1women·posted 7 months ago by u/bastian_eriksen

6 months in and fertility is still the thing I get wrong

PCOS

Long-ish post, sorry. tl;dr at the bottom.

I have been tracking PCOS against eGFR for 13 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here.

Caveats up front: one person, one lab, one assay, no control, and I changed my training in the middle of it, which was stupid.

tl;dr: probably real, definitely smaller than the threads imply, and not worth reorganising your week around.

0 up / 0 down48% upvoted6 commentsid 8k4ws417 Dec 2025

6 comments

6 in this archive, depth 5

best — the order this archive was captured in

u/rina_sobczak5 points·7 months ago·edited

no cycle-tracking data with identifying details

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u/milan_wikstrom2 points·7 months ago

Not convinced. The evidence does not support that reading.

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u/bastian_eriksenOP-29 points·7 months ago

perimenopause and menopause weight physiology

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u/ismael_chukwu1 point·7 months ago·edited

hormonal contraception interactions are speculative

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u/devils_advocate_d1 point·7 months ago

Strongly agree. Cycle changes are documented.

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u/bastian_aalto1 point·7 months ago

cycle changes are real and under-researched

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About c/glp1women

The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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c/glp1women rules
  1. Pregnancy and trying-to-conceive questions get a clinician pointer, not community advice.
  2. Contraception interaction claims need a citation.
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