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[Meta] the method development rule is doing its job and people should stop complaining
method development. That is the whole post, but I will justify it. Everything else people worry about in c/dosinglogs is downstream of it. Titration speed, early fullness, the endless dose arguments — most of it resolves if you sort method development out first, and almost nobody does. I say this having got it wrong…
chromatogram or it did not happen
[removed]250 points·2 years ago
[removed by moderator]
Yeah, the chromatogram profile matters more than the headline number.
the detector wavelength matters more than people think
integration decision on a shoulder changes your number by half a point on its own
area% and mass% are not the same and this whole post conflates them
[removed by moderator]
Yes, exactly this, and it is the bit that took me 95 weeks to accept.