[Meta] the method development rule is doing its job and people should stop complaining
method development. That is the whole post, but I will justify it. Everything else people worry about in c/dosinglogs is downstream of it. Titration speed, early fullness, the endless dose arguments — most of it resolves if you sort method development out first, and almost nobody does. I say this having got it wrong…
The confident tone is doing a lot of work that the evidence is not.
integration decision on a shoulder changes your number by half a point on its own
Small correction: the trial was 2 weeks, not 25. Does not change your point but people will quote it.