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c/hplc·submitted 2 years ago by u/honest_syringe_2025

the integration thing finally clicked for me and I want to write it down

Labbranch of 7 comments

Been lurking in c/t2dglp1 for about 16 months and finally have something worth posting. Short version: week 72, 10mg, and LC-MS is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 11 threads, and the answers split roughly down the middle. What I actually want to know is…

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This branch

7 comments, started 2 years ago
u/sig_figs_samMOD690 points·2 years ago

Removed a chain here. The rule is one line long and it is not negotiable.

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u/peak_area_peteanalytical200 points·2 years ago·edited

a round-robin on baseline integration would be genuinely useful

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u/blunt_coldbox_2024371 points·2 years ago

Detection wavelength? gradient and that changes at different wavelengths.

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u/downvote_magnet432 points·2 years ago

Not to be pedantic but LC-MS and method development are being used interchangeably and they are not interchangeable in real life.

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u/lina_novak291 points·2 years ago

two labs, two different baselines, two different purity numbers, both honest

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u/yara_boateng99 points·2 years ago

This is the correct method framing. Column and gradient are load-bearing fields.

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u/quiet_reader_99181 points·2 years ago

related substances are where the story lives, not the main peak

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